Sherlock Holmes: The Case of the Silver Earring (known in North America as Secret of the Silver Earring and as Sherlock Holmes: The Silver Earring) is a video game developed by Frogwares and published in 2004 for Microsoft Windows by Digital Jesters in Europe and Ubisoft in North America. While the game is "inspired by The Adventures of Sherlock Holmes", it uses an original plotline — set in London in 1897 — and allows the player to investigate a murder as Sherlock Holmes and Dr. John H. Watson. A version for Wii was also released in Europe in 2011. By 2010, Secret of the Silver Earring had sold 500,000 copies worldwide.

The second in the Sherlock Holmes series of adventure games developed by Frogwares, it was preceded by the 2002 game Sherlock Holmes: The Mystery of the Mummy, and was followed by Sherlock Holmes: The Awakened in 2007. The game acts as a prequel to Mystery of the Mummy - despite being released two years after the earlier game, it is actually set two years earlier (in 1897 as opposed to 1899).